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Early life programming of childhood health: a nutritional and epigenetic investigation of adiposity and bone, cardiometabolic, neurodevelopmental and respiratory health ALPHABET

This project is under the call ERA HDHL - Biomarkers for Nutrition and Health.
The aim of the project is to advance the state-of-the-art by significantly expanding the knowledge base regarding interactions between biomarkers of diet, epigenetics and
offspring health. Utilising biological samples and data from existing European longitudinal birth cohorts at the international forefront of lifecourse epidemiology we will investigate the complex relationships between maternal diet (defined by dietary quality and a novel index of dietary inflammatory potential), offspring health outcomes (including adiposity, bone, cardiometabolic, respiratory and neurodevelopmental health) and epigenetic patterns (DNA methylation) from birth throughout childhood. Better understanding of nutritional and epigenetic biomarkers of offspring health will afford opportunities to refine dietary exposure measures and to aid development of more effective evidence-based public health strategies with an emphasis on advocating a healthy diet in pre-pregnancy,  pregnancy and early postnatal life, to reduce obesity, improve health and attenuate
development of a range of adverse health outcomes in future generations.

Duration of the project: 22.02.2017 - 21.10.2019
Project coordinator: School of Public Health, Physiotherapy and Sports Science, University College Dublin, Ireland
Head of the NIOM team involved in the project realization: Kinga Polańska, PhD: Kinga.Polanska@imp.lodz.pl

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